Binaree Tissue Clearing Kit

Binaree

Revolutionize your research with our Binaree Tissue Clearing Kit – a truly adaptive approach to deep tissue imaging.

  • The intact tissue clearing kit without the dedicated equipment.
  • The adaptive one solution for multiple tissue types and immunostaining.
  • 3D analysis for the deep tissue sample without slide section.

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Description

Product Highlights

  • Multiple-purpose tissue clearing kit: various tissue types and immunostaining.
  • Tipping point technology for Immunostaining: The first commercial-level solution for more than 1mm thickness sample in the world. It overcomes the technical limitation of the penetration and gets more specific biological results than before.
  • Customisable Kit: Our kit can make immunostaining tissue as part or whole: Brain, Eye and Pancreas and are also available precisely. Customized kit for Organoid and Spheroid available.

Got large volume sample? – Try our Binaree Tissue Clearing Rapid! It is the rapid tissue clearing system for the large volume sample, also known as the fastest solution in the market. You can finish a whole mouse brain tissue clearing  in 6 hours. Check here

What does it contain

HRTC-012 Solution

HRTC-012 is an ideal kit for deep tissue clearing of 3-dimensional high-resolution imaging. It is simple as a clearing process, intact as preservation of cell structure, non-harmful as no organic solvent-based, and reproducible-no special equipment. It shows a low fluorescence loss rate known as low fluorescence quenching after clearing compared to the typical tissue clearing methods. 

Mounting solution (HRMO-006)

Binaree Tissue Clearing Mounting solution (as called as Mounting solution) is optimized for the Binaree Tissue Clearing method. The Reflective Index (RI) is 1.46. In particular, it has excellent fluorescence retention when clearing endogenic fluorescence and immunolabeled tissue. This product is not crystalized even at low temperatures, so it can stably image tissue for a long time. It is not an organic solvent base, so it can be used safely with the microscope.

Highlights 

  • Now, you can do the multiple-purpose tissue clearing with HRTC-012 and Mounting Solution: various tissue types and immunostaining.
  • Improve clearing speed for the immunostaining: HRTC-012 is faster than the previous HRTI product in the clearing process for immunostaining. e.g., In 1 mm depth sample, the previous HRTI product takes 6 days, but the new HRTC-012 takes 1 day.

Binaree Tissue Clearing Solutions – High-resolution mapping of three-dimensional (3D) imaging of intact brains has been used as a viable approach to visualizing neuroanatomical data. In particular, this imaging allow the spatial location or overall morphology of cells of interest within tissue to be extended beyond the sculpted biological and medical information using time-consuming sectioning methods into holistic information. The recently developed tissue clearing technique combines with optical imaging equipment such as confocal and light-sheet microscopy and imaging programs to enable the identification of biological information in 3D directly without the need to collate 2D imagines.

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View the tissue clearing workflow and 3D imaging process below. Read Binaree’s latest news and case studies here.

Binaree, Inc. is developing and commercializing innovative tools and enables three-dimensional investigation of a tissue’s molecular and structural information through rapid clearing and immunostaining of tissues.

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