The Evolution in Freely-Behaving Imaging and Optogenetics Technology
To offer neuroscientists the ability to stimulate and visualize individual neurons in freely-behaving animals, Mightex’s engineers went back to the drawing board and pioneered a new path in the in vivo calcium imaging field. Instead of miniaturizing and placing the microscope on the animal – thereby limiting the microscope’s features and the animal’s behaviour – we kept the microscope off the animal’s head by using an imaging fiber.
By keeping the microscope away from the animal’s head, the OASIS Implant accomplishes 2 main goals:
Investigate Multiple Brain Regions Simultaneously
Neurons project to different parts of the brain, and neuroscientists are interested in understanding how these connections affect behaviour. The OASIS Implant uses a bifurcated imaging fiber that connects to multiple GRIN lenses, allowing researchers to perform imaging and optogenetics in multiple brain regions simultaneously.
Fiber Photometry and Cellular-Resolution Calcium Imaging with One System
The OASIS Implant is capable of both population-level calcium imaging using fiber photometry and cellular-resolution calcium imaging. Perform exploratory research using fiber photometry, and delve in deeper to understand the patterns of individual neuron firing.
Mightex offers a one-stop shop for your in vivo calcium imaging and optogenetics research needs. Our full-solution pipeline from hardware and software, to experimental optimization and data processing tools is designed to facilitate and catalyze your research findings. We are also able to offer custom solutions for bespoke research needs.
Contact our expert team of application and development scientists today to learn more!
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