Contactless conductivity detection can be used for virtually all charged species: inorganic anions and cations, as well as organic ions, such as carboxylic acids, amines, amino acids, peptides, proteins, DNA fragments, antibiotics and many other pharmaceutical compounds. Tagging or other modification of the analytes is usually NOT required, while limits of detection are often comparable to, or sometimes even better, than UV-visible absorption techniques.
The C4D system comprises of a hardware unit and headstage.